acetyl hexapeptide-37

Acetyl hexapeptide-37 is a synthetic peptide composed of the amino acids alanine, proline, serine and glycine. This peptide works with the water channels (known as aquaporins) in skin’s surface layers, helping to provide adequate, balanced hydration between skin’s layers, a process which alleviates signs of dry, dehydrated skin.

Although there isn’t independent research confirming the effectiveness of this peptide on skin, the supplier (Lipotec) has made the results of their research available in a lengthy Technical Report that’s supported by third-party studies. Between this information and the wider field of published scientific research on peptides for skin, we feel confident recommending this peptide, particularly for dehydrated skin.

See peptides amino acid

Back to Ingredient Dictionary

About the Experts

Paula Begoun is the best-selling author of 20 books about skincare and makeup. She is known worldwide as The Cosmetics Cop and creator of Paula’s Choice Skincare. Paula’s expertise has led to hundreds of appearances on national and international radio, print, and television including:

The Paula's Choice Research Team is dedicated to busting beauty myths and providing expert advice that solves your skincare frustrations so you can have the best skin of your life!