N-hydroxysuccinimide is a synthetic ingredient used in cosmetics as an ester to soften and condition skin. It’s also a reagent, a substance used to trigger a reaction that leads to a new substance, such as peptides and polymers.

References for this information:

Journal of the American Chemical Society, August 2018, pages 9,374-9,378
Journal of Biomedical Materials Research, July 2009, pages 70-81
Bioconjugate Chemistry, November-December 2001, pages 1,085-1,088

See ester

Back to Ingredient Dictionary

About the Experts

Paula Begoun is the best-selling author of 20 books about skincare and makeup. She is known worldwide as The Cosmetics Cop and creator of Paula’s Choice Skincare. Paula’s expertise has led to hundreds of appearances on national and international radio, print, and television including:

The Paula's Choice Research Team is dedicated to busting beauty myths and providing expert advice that solves your skincare frustrations so you can have the best skin of your life!