CLINICAL 1% Retinol Treatment
Based on 776 reviews
A potent and uniquely formulated retinol solution that hydrates and delivers remarkable anti-ageing benefits with a controlled-release delivery system to allow for even, consistent absorption.

CLINICAL 1% Retinol Treatment

Based on 776 reviews
A potent and uniquely formulated retinol solution that hydrates and delivers remarkable anti-ageing benefits with a controlled-release delivery system to allow for even, consistent absorption.
  • Advanced hydrating complex absorbs quickly
  • Diminishes the appearance of wrinkles, fine lines
  • Light lotion texture delivers powerful results
  • Use after cleansing, toning & exfoliating skin
Skin Types:
All Skin Types
Wrinkles, Anti-Ageing
    30 ml
    Travel Size...
Why is it different?
Combined with potent antioxidants, CLINICAL 1% Retinol Treatment is a specially formulated light lotion that absorbs quickly and goes to work immediately to enhance hydration and diminish the appearance of wrinkles, fine lines, and uneven skin tones. Licorice, oat extract and other soothing ingredients help to calm redness.
What does it do?
Goes to work immediately to visibly refine pore size and diminish the appearance of wrinkles, fine lines and uneven skin tone. The light lotion formula is supplemented with nourishing licorice extract, oat extract and other soothing plant extracts to calm skin and ease redness. You’ll be amazed at how much younger-looking, firmer, and radiant your skin will look and feel.
How to use

Limit initial use to three times per week; gradually increase frequency to every other night, then finally each evening as tolerated. Apply a pea-sized amount amount after cleansing and toning. Carefully avoid the lips, eyes (including eyelids) and corners of the eyes. Can be used on the perimeter of the orbital bone if desired. To minimise irritation, try combining with 2-3 drops of Resist Moisture Renewal Oil Booster.

Note: Some people may experience a delayed sensitised reaction to 1% retinol. Do not assume that if no reaction is seen after a few applications that you can apply this product more frequently. Pay close attention to how your skin responds and adjust usage accordingly.

If sensitisation occurs (redness, flaking, tenderness, or drying of skin), reduce frequency of use or mix one pump of the Clinical 1% Retinol Treatment with your favourite Paula’s Choice serum or PM moisturiser. If sensitisation persists, discontinue use. Protect skin daily with sunscreen rated SPF 15 or greater.

Show details

Journal of Cosmetic Dermatology, March 2016, issue 1, pages 49-57

Journal of Drugs in Dermatology, March 2015, issue 3, pages 271-280

Phytotherapy Research, August 2015, issue 8, pages 1117-1122

Skin Research and Technology, August 2013, issue 3, pages 291-298

Inflammopharmacology, October 2011, issue 5, pages 245-254

Journal of Cosmetic Dermatology, December 2008, issue 4, pages 281-289

Indian Journal of Dermatology and Venereology, March-April 2012, issue 2, pages 142-145

American Journal of Clinical Dermatology, 2003, issue 2, pages 107-129

Evidence Based Complementary Alternative Medicine, 2013, volume 2013, article 827248

Pharmacology and Physiology, March-April 2005, issue 2, pages 81-87

Dermato-Endocrinology, July 2012, issue 3, pages 253-258

Indian Dermatology Online Journal, April-June 2013, issue 2, pages 143-146

Product Ingredients Water (Aqua), Dimethicone (skin-softening), Glycerin (skin-replenishing), Butylene Glycol (hydrating), Isononyl Isononanoate (emollient), Castor Isostearate Succinate (skin-softening ), Glyceryl Stearate (texture enhancer), C12-15 Alkyl Benzoate (emollient), Dimethicone Crosspolymer (texture enhancer), PEG-33 (stabilizer), Polysorbate 20 (texture enhancer), Behenyl Alcohol (texture enhancer), PEG-100 Stearate (texture enhancer), Pentaerythrityl Tetraisostearate (stabilizer), Polymethylsilsesquioxane (texture enhancer), Tetrahexyldecyl Ascorbate (vitamin C/antioxidant), Retinol (skin-restoring), Ceramide NG (skin-replenishing) , Palmitoyl Tetrapeptide-7 (skin-restoring), Palmitoyl Hexapeptide-12 (skin-restoring), Sodium Hyaluronate (skin-replenishing ), Dipotassium Glycyrrhizate (antioxidant plant extracts/skin-soothing), Glycyrrhiza Glabra Root Extract (licorice extract/antioxidant/skin-soothing), Avena Sativa Kernel Extract (oat extract/antioxidant/skin-soothing), Arctium Lappa Root Extract (burdock extract/antioxidant/skin-soothing), Salix Alba Bark Extract (willow bark extract/antioxidant/skin-soothing), Glycine Soja Sterols (antioxidant/skin-softening ), Lecithin (skin-restoring), Allantoin (skin-soothing), Tocopheryl Acetate (vitamin E/antioxidant), Hydrolyzed Soy Protein (antioxidant/skin-softening), Sorbitan Laurate (texture enhancer), Acetyl Dipeptide-1 Cetyl Ester (skin-soothing), Disodium EDTA (stabilizer), Hydroxyethylcellulose (texture enhancer), Palmitoyl Tripeptide-1 (skin-restoring), Sodium Hydroxide (pH adjuster), Tribehenin (emollient), Caprylyl Glycol (skin-softening), Ethylhexylglycerin (skin-softening), Pentylene Glycol (hydrating), PEG-75 Shea Butter Glycerides (emollient), PPG-12/SMDI Copolymer (stabiliser), PEG-10 Phytosterol (fatty acid-based emollient), PEG-8 Dimethicone (skin-softening), PEG-14 (texture enhancer), Magnesium Aluminum Silicate (texture enhancer), Arachidyl Glucoside (texture enhancer), Arachidyl Alcohol (texture enhancer), Sclerotium Gum (texture enhancer), Carbomer (gel-based texture enhancer), Phenoxyethanol (preservative), Benzoic Acid (preservative).

Ratings & Reviews

Great product


I have endometriosis which leads to some jawline acne which can scar. I also get eczema on my face due to food allergies. I bought this in the sale three weeks ago and was nervous to try it in case I broke out. For now, I use it every third night and will progress to ever second night. I'm 27 so can't say that it fixes wrinkles as I don't have any, but I am sure with regular retinol use I will age well. FYI - I started using retinol when I was about 24 AND I am religious about wearing sunscreen. I noticed just yesterday how amazing my skin is looking. I had zero bad reactions to this product, and it's softened and changed my skin tone for the better. I still have a couple of breakouts but the scarring doesn't look aggressive. I even stopped using concealer and can just put my foundation on and I'm satisfied the scars and breakouts are quite hidden. I don't tend to react to skincare as my bad eczema breakouts are food related, so I don't know if everyone will have the same experience but I'm now sold on this. Will buy it over and over.




100% works.


This product again delivered, def helped my skin to look brighter, luminous, fine lines less visible, I've regained my confidence. Dreaded turning 40, now embracing my new found skim confidence. This product I have purchased before and will keep purchasing. Thank you Paula


Blue mountains


Will keep buying


This product is amazing, I can def see the difference. My skin has never looked better


Blue Mountains


Visible improvement


This has made a visible difference to my adult acne. I am breaking out much less frequently and my skin tone has improved. I started out using it 2 nights a week, gradually working up to every other night and have not had any irritation at all. Recommend!




Consider using with a moisturiser for best results


By far the most effective product I've used for improving crepey skin on my neck. I need to use it with a moisturiser to reduce the chance of irritation but otherwise it is fabulous. Good for the face as well!




This Retinal product works


Love it, it did not irritate my skin. I also mix it with any serum, don;t put it directly to my skin. I can see a great result.


Sausalito Ca


Love it


It is really hard to say that a particular product works, since I use a lot and different brands. But with this one, that I apply at night, I see the difference the next morning. My skin is so smooth and silky, unbelievable. Definitely a must have!




Amazing product, fast results


I LOOOOVE this product, perfect smell and texture. Finishing my 2nd bottle now. I started off with 3 times/week and increased it to every night. Did not experience any irritation. It's pricey but last for long time and results are amazing. Helps with fine lines wrinkles and texture & I wake up every morning with silky smooth skin. The best is that people notice the difference. I also figured out to pop off the gold ring to get a couple more use out of it. Paula please don't change this product.


Auckland New Zealand


I have glowing and supple skin from this!


I'm 38 years old and have sensitive skin. I'd honestly never really gotten complimented on my skin before, until I started using Paula's products, and can tell there's a huge difference in it's condition. My skin used to have a sort of dull cast to it that began in my mid-thirties. Now I get complimented often and people ask what I use every time. If your skin can tolerate a retinol, I highly recommend this. Just make sure you follow the instructions. It took about three weeks for me to be able to apply this daily. A heavy moisturizer helped, but now my skin's adapted.




The best


The best retinol treatment I've ever used. I've been using this for years and it's fabulous. Highly recommend it!!!


Tampa, Fl



4.2 776