CLINICAL PRO Retinaldehyde Treatment

PRO Retinaldehyde Treatment

Full Size | 30 ml
A$98.00
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CLINICAL PRO Retinaldehyde Treatment
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CLINICAL PRO Retinaldehyde Treatment
CLINICAL

PRO Retinaldehyde Treatment

  • Clears Blemishes
  • Age Prevention
  • Fades Dark Spots

A high-potency retinoid treatment that delivers advanced results for clear, luminous skin.

  • 0.1% Retinaldehyde (Retinal): Closest to prescription-strength retinoid delivers advanced results
  • High potency, gentle release formula: Calcium-encapsulated retinoid minimises irritation
  • Natural bioactive yellow: Retinaldehyde has a naturally vibrant hue
A$98.00
Benefits

CLINICAL Pro Retinaldehyde Treatment is a first-of-its-kind retinoid that is a direct precursor to retinoic acid—meaning it needs fewer conversion steps compared to retinol, making it gentler on skin. Encapsulated in calcium, retinaldehyde communicates with skin’s surface for clearer, smoother skin with minimised irritation. Antioxidant-rich pomegranate peel helps support healthy collagen and soothes.

Next-gen retinoid supports cell renewal & promotes clear, blemish-free skin with clinically proven encapsulated retinaldehyde & pomegranate peel. Visibly improves texture & restores luminosity.

The bottle for this full-sized product is made from 96% recycled material (excluding cap and orifice reducer).
How To Use

STEP 4: TREATMENT

When To Apply

Start with 3x/week & gradually increase frequency to every night as tolerated. Apply 1–2 pumps over face & neck, avoiding contact with eyes. Blend thoroughly. For daytime, follow with sunscreen.

How To Apply

Start with 3x/week & gradually increase frequency to every night as tolerated. Apply 1–2 pumps over face & neck, avoiding contact with eyes. Blend thoroughly. For daytime, follow with sunscreen.
Ingredients

Key Ingredients

  • Retinal
  • Simmondsia Chinensis (Jojoba) Seed Oil
  • Albatrellus Confluens (Mushroom) Extract
  • Punica Granatum Pericarp Extract
  • Aqua/Water/Eau
See All Ingredients
  • Caprylic/Capric Triglyceride
  • Polyglyceryl-2 Stearate
  • Propanediol
  • Polyglyceryl-3 Diisostearate
  • Sodium Stearoyl Glutamate
  • Tocopherol
  • Tocopheryl Acetate
  • Saccharomyces Ferment Filtrate
  • Glyceryl Stearate
  • Stearyl Alcohol
  • Hydroxyapatite
  • Butylene Glycol
  • Cetyl Glyceryl Ether
  • Ricinus Communis (Castor) Seed Oil
  • Sodium Polyacrylate
  • Isopropyl Myristate
  • Hydroxyacetophenone
  • Sodium Phytate
  • Xanthan Gum
  • Glycerin
  • Hydroxystearic Acid
  • 1, 2-Hexanediol
  • Sorbitan Oleate
  • Naringin
  • Citric Acid
  • Titanium Dioxide

Paula's Choice is dedicated to maintaining the accuracy of the ingredient lists on this website. However, because ingredients are subject to change, we cannot guarantee that these lists are error-free. For an accurate listing of ingredients in each product, please refer to your product packaging.
Research
  • Advances in Therapy, October 2022, pages 5,351–5,375
  • Polymers, May 2021, pages 1–22
  • Pharmaceuticals, August 2020, pages 1–22
  • International Journal of Cosmetic Science, April 2019, pages 240–256
  • Journal of Drugs in Dermatology, March 2019, pages 255–260
  • American Journal of Clinical Dermatology, January 2019, pages 345–365
  • Journal of Cosmetic Dermatology, September 2021, pages 2,874–2,879; and June 2018, pages 471–476
  • Clinical Interventions in Aging, December 2006, pages 327–348
  • Journal of Ethnopharmacology, October 2005, pages 311–317
  • |Free Radical Biology and Medicine, June 1996, pages 761–769

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FAQs

Who is the target customer for CLINICAL Pro Retinaldehyde Treatment?

The ideal client for this treatment is someone in their late 20s through early 60s who is seeing fine lines, wrinkles, loss of firmness, enlarged or clogged pores, rough or bumpy texture, excess oily, and/or post-blemish marks and is even suitable for those with blemish-prone skin.

How is the CLINICAL Pro Retinaldehyde Treatment different from other Paula’s Choice retinoid products?

The main differences between Paula’s Choice retinoid products are their texture, key ingredients and targeted concerns. The CLINICAL Pro Retinaldehyde Treatment is a fast-absorbing light lotion that is formulated with retinaldehyde (retinal) to address multiple signs of ageing, as well as rough, bumpy texture and blemish/pore-related concerns. It is considered a professional strength, yet gentle, option. If you have had increased sensitisation from using the CLINICAL 1% Retinol Treatment in the past, you may want to consider trying the CLINICAL PRO Retinaldehyde Treatment to see how your skin responds to this formula.

Is the retinoid in this formula encapsulated?

Yes, our innovative retinoid formula utilises calcium microparticles (hydroxyapatite), which act as a protective shell for the retinaldehyde, preventing degradation from light and air. This controlled release mechanism maintains stable retinaldehyde levels in the skin, limiting irritation and optimising benefits.

Why is the CLINICAL Pro Retinaldehyde Treatment yellow? Will it stain my skin or fabrics?

The bright yellow colour comes from retinal (vitamin A) in its purest form. This golden hue reflects the high concentration of retinaldehyde in the formula. It also helps guide precise application, especially around delicate areas such as the eyes.

You may notice a slight yellow tint on your skin upon application—this is completely normal and fades quickly as the product absorbs. It won’t stain your skin or fabrics.

To avoid any potential transfer—especially to light-coloured bedding—apply earlier in the evening and allow the product to fully absorb before your skin touches fabric. These simple steps help ensure you get the full benefits of the treatment without leaving a trace.

Is the CLINICAL Pro Retinaldehyde Treatment for advanced retinoid users only? Can someone new to retinoids try it?

For those with concerns like lines, wrinkles, rough texture, blemishes and pore congestion, the CLINICAL PRO Retinaldehyde Treatment is an effective choice, although it may not be the best option for retinoid beginners. Given its potency, start with once or twice-weekly application, gradually increasing frequency to avoid irritation. Consider a patch test beforehand to gauge skin sensitivity.

Can the CLINICAL Pro Retinaldehyde Treatment be used with prescription retinoids or anti-blemish products?

Yes, however, before doing so, consult your healthcare provider and follow their advice. They may advise you to apply your prescription product at a separate time of day from this treatment until you see how your skin responds to the retinoid blend our formula contains. If you find this combination causes undesirable side effects, discontinue use and inform your healthcare provider..

Is the CLINICAL Pro Retinaldehyde Treatment good for sensitive skin?

Yes, this formula may be suitable for sensitive skin . While retinaldehyde is considered a high-strength retinoid, it is generally tolerated well. In addition, we’ve added soothing ingredients like pomegranate peel extract, jojoba seed oil and mushroom extract to help minimise potential discomfort and/or irritation. Always remember to begin slowly, limiting initial use to once or twice weekly, then gradually increasing frequency. Patch test for very sensitive skin. Be cautious of overuse, which can lead to dryness, sensitivity and breakouts. You can also opt for a lower strength retinoid and consistent moisturising to mitigate these effects.

Can I use the CLINICAL Pro Retinaldehyde Treatment while pregnant or breastfeeding?

Even though the systemic absorption of topically applied over-the-counter retinoids is low, we recommend that you avoid prescription retinoids (Renova™, Retin-A™, Differin™, Tazorac™ and generic tretinoin) and over-the-counter products with retinol and its derivatives due to their relation to prescription retinoids. Consider switching to an anti-ageing product that does not contain retinol or its derivatives (retinyl retinoate, retinaldehyde, retinyl linoleate, retinyl propionate or hydroxypinacolone retinoate). For additional ingredient questions during pregnancy, be sure to consult with your doctor and follow their recommendations and read our Expert Advice Article to learn more about skin care products that are safe to use during pregnancy.