CLINICAL 1% Retinol Treatment
Based on 41 reviews


CLINICAL 1% Retinol Treatment
A potent and uniquely formulated retinol solution that hydrates and delivers remarkable anti-ageing benefits with a controlled-release delivery system to allow for even, consistent absorption.

CLINICAL 1% Retinol Treatment

Based on 41 reviews


A potent and uniquely formulated retinol solution that hydrates and delivers remarkable anti-ageing benefits with a controlled-release delivery system to allow for even, consistent absorption.
  • Advanced hydrating complex absorbs quickly
  • Diminishes the appearance of wrinkles, fine lines
  • Light lotion texture delivers powerful results
  • Use after cleansing, toning & exfoliating skin
Skin Types:
All Skin Types
Wrinkles, Anti-Ageing

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    30 ml
    Travel Size...

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Additional Information

Why is it different?
Combined with potent antioxidants, CLINICAL 1% Retinol Treatment is a specially formulated light lotion that absorbs quickly and goes to work immediately to enhance hydration and diminish the appearance of wrinkles, fine lines, and uneven skin tones. Licorice, oat extract and other soothing ingredients help to calm redness.
What does it do?
Goes to work immediately to visibly refine pore size and diminish the appearance of wrinkles, fine lines and uneven skin tone. The light lotion formula is supplemented with nourishing licorice extract, oat extract and other soothing plant extracts to calm skin and ease redness. You’ll be amazed at how much younger-looking, firmer, and radiant your skin will look and feel.
How to use

Limit initial use to three times per week; gradually increase frequency to every other night, then finally each evening as tolerated. Apply a pea-sized amount amount after cleansing and toning. Carefully avoid the lips, eyes (including eyelids) and corners of the eyes. Can be used on the perimeter of the orbital bone if desired. To minimise irritation, try combining with 2-3 drops of Resist Moisture Renewal Oil Booster.

Note: Some people may experience a delayed sensitised reaction to 1% retinol. Do not assume that if no reaction is seen after a few applications that you can apply this product more frequently. Pay close attention to how your skin responds and adjust usage accordingly.

If sensitisation occurs (redness, flaking, tenderness, or drying of skin), reduce frequency of use or mix one pump of the Clinical 1% Retinol Treatment with your favourite Paula’s Choice serum or PM moisturiser. If sensitisation persists, discontinue use. Protect skin daily with sunscreen rated SPF 15 or greater.

Show details

Journal of Cosmetic Dermatology, March 2016, issue 1, pages 49-57

Journal of Drugs in Dermatology, March 2015, issue 3, pages 271-280

Phytotherapy Research, August 2015, issue 8, pages 1117-1122

Skin Research and Technology, August 2013, issue 3, pages 291-298

Inflammopharmacology, October 2011, issue 5, pages 245-254

Journal of Cosmetic Dermatology, December 2008, issue 4, pages 281-289

Indian Journal of Dermatology and Venereology, March-April 2012, issue 2, pages 142-145

American Journal of Clinical Dermatology, 2003, issue 2, pages 107-129

Evidence Based Complementary Alternative Medicine, 2013, volume 2013, article 827248

Pharmacology and Physiology, March-April 2005, issue 2, pages 81-87

Dermato-Endocrinology, July 2012, issue 3, pages 253-258

Indian Dermatology Online Journal, April-June 2013, issue 2, pages 143-146

Product Ingredients Water (Aqua), Dimethicone (skin-softening), Glycerin (skin-replenishing), Butylene Glycol (hydrating), Isononyl Isononanoate (emollient), Castor Isostearate Succinate (skin-softening ), Glyceryl Stearate (texture enhancer), C12-15 Alkyl Benzoate (emollient), Dimethicone Crosspolymer (texture enhancer), PEG-33 (stabilizer), Polysorbate 20 (texture enhancer), Behenyl Alcohol (texture enhancer), PEG-100 Stearate (texture enhancer), Pentaerythrityl Tetraisostearate (stabilizer), Polymethylsilsesquioxane (texture enhancer), Tetrahexyldecyl Ascorbate (vitamin C/antioxidant), Retinol (skin-restoring), Ceramide NG (skin-replenishing) , Palmitoyl Tetrapeptide-7 (skin-restoring), Palmitoyl Hexapeptide-12 (skin-restoring), Sodium Hyaluronate (skin-replenishing ), Dipotassium Glycyrrhizate (antioxidant plant extracts/skin-soothing), Glycyrrhiza Glabra Root Extract (licorice extract/antioxidant/skin-soothing), Avena Sativa Kernel Extract (oat extract/antioxidant/skin-soothing), Arctium Lappa Root Extract (burdock extract/antioxidant/skin-soothing), Salix Alba Bark Extract (willow bark extract/antioxidant/skin-soothing), Glycine Soja Sterols (antioxidant/skin-softening ), Lecithin (skin-restoring), Allantoin (skin-soothing), Tocopheryl Acetate (vitamin E/antioxidant), Hydrolyzed Soy Protein (antioxidant/skin-softening), Sorbitan Laurate (texture enhancer), Acetyl Dipeptide-1 Cetyl Ester (skin-soothing), Disodium EDTA (stabilizer), Hydroxyethylcellulose (texture enhancer), Palmitoyl Tripeptide-1 (skin-restoring), Sodium Hydroxide (pH adjuster), Tribehenin (emollient), Caprylyl Glycol (skin-softening), Ethylhexylglycerin (skin-softening), Pentylene Glycol (hydrating), PEG-75 Shea Butter Glycerides (emollient), PPG-12/SMDI Copolymer (stabiliser), PEG-10 Phytosterol (fatty acid-based emollient), PEG-8 Dimethicone (skin-softening), PEG-14 (texture enhancer), Magnesium Aluminum Silicate (texture enhancer), Arachidyl Glucoside (texture enhancer), Arachidyl Alcohol (texture enhancer), Sclerotium Gum (texture enhancer), Carbomer (gel-based texture enhancer), Phenoxyethanol (preservative), Benzoic Acid (preservative).

Ratings & Reviews

Noticeable results.


Almost immediate results. I woke up with fresh dewy skin. Be warned though - do not overdo it. You need to build up a tolerance to Retionol otherwise you will experience some redness and irritation. Slowly increase applications over weeks. I really really love this stuff and am impressed with the results on my skin. Will definitely repurchase.


New Zealand


Brilliant product - essential for anti-aging skincare


I am 50 and people genuinely believe I am 10 years younger, even after spending a lifetime outdoors. I have never used botox, fillers, professional facials, etc. The secret is slathering yourself in sunblock everyday plus having a a regular skincare routine (face, neck, décolletage) using products with the right amount of active ingredients and packaged correctly so they don't go off. This product ticks all the boxes. My skin is smooth, line free and appears poreless. I use it every second night and wake up looking like I have had the best slept, which is very rare. I don't agree with those criticising the packaging, claiming it causes product waste. When you can no longer pump the cream out of the bottle, the gold capping around the top of the bottle can be easily prized off, then pull the tube cylinder out of the purple container, unscrew the lid and you have a good few applications left, accessed with an earbud. No waste. The packaging is designed to avoid sunlight and air spoiling the retinol. I challenge anyone to find a retinol product that is available off the shelf i.e no prescription required, with a retinol strength greater than 1% , stored in correct packaging for a better price. Please never stop making this stuff.


Narrabundah Canberra Australia


This product is great


I am hesitant about skincare claims so bought the trial size. My skin was dry with patches that seemed course, large pores on my nose, fine wrinkles, makeup clumped on my skin, redness. I have been using 2 products that have turned my skin around. Each night I apply a generous amount of skin perfecting 8% aha lotion (not heaps) then every second morning I apply this retinol 1%. I started every few days and built up to daily but t I didn't have any reaction. My skin's looking and feeling good and the makeup looks great on my skin. I wanted to not like this product because it's expensive but have decided it's worth it after a month of trial. I don't use other products.




Clinical 1% retinol treatment


Nice product but needs to be used for quite some time before you see results.The packaging is horrid as you can't get all the product out as you near the end.I threw it away with at least two more nights use in it which I couldn't get out.Very disappointed as it isn't cheap.I have noticed that others have complained,hope you have fixed the problem Paula.



My Can't Live Without Product!!!!!


I can't speak highly enough about this product, my skin glows, less fine lines, more even toned skin, make up even looks better now as my skin is less dry and more radiant. The only negative is when the bottle runs out. Take my word for it this product works. Love it better than air water and coffee


Blue Mountains NSW Aus


Immediate results


I noticed immediate results. I have oily, sensitive and rosacea prone skin but this was brilliant. I did notice mild flaking (not noticeable to others) but I'm sure by either reducing the frequency or diluting with a moisturiser will suffice. Looking forward to seeing my skin change over the next few weeks and months. Will definitely repurchase.




Best value strong retionl product on the market


I have tried many retinol products over the last 4 years and I always seem to keep coming back to this one. In terms of the amount of retionl and other beneficial ingredients there is not really anything else out on the market that holds a candle to this (unless you want to pay between $100 - $200). My skin tolerates use of this product daily, which has not been the case with some other 1% retinol products that I have tried. I would happily pay full price for this product.


Sydney NSW




My friend bought me this as a gift. It's great. The best anti wrinkle I've tried. My skin definitely feels smoother and tighter with less wrinkles. I use mine every night. The bottle lasts me 3 months. I'm about to order myself a second bottle






I use this every 3rd night approx with no irritations. My skin is glowing and is looking healthier each week. I will continue to use this product as I have had nothing but positive reactions! Thanks P.C






I'm onto my second bottle of this and it has changed my skin so much. I started using it because I was getting hormonal cystic acne as well as more moderate acne generally, and it has ameliorated my cysts so much I barely ever get them (only if i'm naughty and drunkenly fall asleep with silicone heavy primer on). It really does dramatically improve hyperpigmentation, acne, fine lines (not that i really have any) huge pores, skin plumpness and probably a ton of other problems i don't have. I haven't had problems with irritation once i got used to it, with the exception of if i put it on my neck, or if i use it with 2% bha then i get flaking so that it looks like my face is peeling off. I have very oily skin but it is pleasant as a moisturiser/treatment and doesn't seem too heavy. probably the only con is the price, but if you can get discounts then it's certainly comparable to also expensive prescription products. All up this is life changing if you have serious skin problems and i would definitely recommend the brand to everyone. even if they don't ask haha.





4.5 41