CLINICAL Niacinamide 20% Treatment

Niacinamide 20% Treatment

Full Size | 20 ml
A$79.00
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CLINICAL Niacinamide 20% Treatment
1/10
1/10
CLINICAL

Niacinamide 20% Treatment

3.8
Rated 3.8 out of 5 stars
34
  • Environmental Protection
  • Minimises Pores
  • Oil Control
A highly concentrated niacinamide (vitamin B3) serum that effectively tightens and minimises the look of enlarged pores and bumps caused by age or sun damage.
  • Dramatically reduces the look of enlarged pores
  • Helps reduce hard, clogged bumps & orange-peel texture
  • Visibly improves blotchy tone & fades post-blemish marks
A$79.00
Product SizeFull Size | 20 ml
Benefits

CLINICAL Niacinamide 20% Treatment features the first-of-its-kind concentration of vitamin B3 that uniquely penetrates skin’s surface to help improve the look of enlarged, stretched pores.

  • Dramatically reduces the look of enlarged pores
  • Helps reduce hard, clogged bumps & orange-peel texture
  • Visibly improves blotchy tone & fades post-blemish marks

Niacinamide has a normalizing ability on the pore lining. This plays a role in helping to keep oil and debris from getting backed up, which leads to clogs and rough, bumpy skin. Learn more about niacinamide benefits.

The bottle for this full-sized product is made from 96% recycled material (excluding cap and orifice reducer).

How To Use

STEP 4: VISIBLY IMPROVE ENLARGED PORES

Apply a few drops of Niacinamide 20% once or twice daily after cleansing, toning, and exfoliating. At night, layer with other treatment products as needed and follow with moisturiser; during the day, finish with a sunscreen rated SPF 15 or greater.

Ingredients

Key Ingredients

  • Water/Aqua/Eau
  • Niacinamide
  • Pentylene Glycol
  • Butylene Glycol
  • Glycerin
See All Ingredients
  • Acetyl Glucosamine
  • Ascorbyl Glucoside
  • Glycyrrhiza Glabra (Licorice) Root Extract
  • Spiraea Ulmaria Extract
  • Portulaca Oleracea Extract
  • Camellia Japonica Flower Extract
  • Epigallocatechin Gallate
  • Boerhavia Diffusa Root Extract
  • Camellia Sinensis Leaf Extract
  • Allantoin
  • Lecithin
  • Pullulan
  • Panthenol
  • Silica
  • Xanthan Gum
  • Sclerotium Gum
  • Propanediol
  • Sodium Phytate
  • Phenoxyethanol
  • Ethylhexylglycerin

Water (Aqua/Eau), Niacinamide, Pentylene Glycol, Glycerin, Butylene Glycol, Acetyl Glucosamine, Ascorbyl Glucoside, Glycyrrhiza Glabra (Licorice) Root Extract, Spiraea Ulmaria Extract, Portulaca Oleracea Extract, Camellia Japonica Flower Extract, Epigallocatechin Gallate, Boerhavia Diffusa Root Extract, Camellia Sinensis Leaf Extract, Allantoin, Lecithin, Pullulan, Panthenol, Silica, Xanthan Gum, Sclerotium Gum, Propanediol, Sodium Phytate, Sodium Hydroxide, Ethylhexylglycerin, Phenoxyethanol. il247v3

Paula's Choice is dedicated to maintaining the accuracy of the ingredient lists on this website. However, because ingredients are subject to change, we cannot guarantee that these lists are error-free. For an accurate listing of ingredients in each product, please refer to your product packaging.

Research
  • Antioxidants, March 2024, pages 1–18
  • Journal of Cosmetic Dermatology, January 2021, pages 304–309
  • Journal of Cellular and Molecular Medicine, September 2019, pages 6,203–6,214
  • Journal of Food Biochemistry, April 2019, ePublication
  • Journal of Pharmacopuncture, March 2019, pages 7-15
  • Experimental Dermatology, February 2019, pages 15–22
  • BMC Complementary and Alternative Medicine, January 2019, ePublication
  • Journal of Ethnopharmacology, March 2018, pages 132-137; and December 2016, pages 627-636
  • Cosmetics, February 2018, pages 10-11
  • Skin Pharmacology and Physiology, June 2014, pages 311-315
  • Cosmeceuticals and Cosmetic Practice, First Edition; 2014, pages 103-111
  • International Journal of Cosmetic Science, October 2013, pages 472-476

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FAQs

What’s the difference between the CLINICAL Niacinamide 20% Treatment and the 10% Niacinamide Booster?

Aside from the concentration of niacinamide (20% vs. 10%), the CLINICAL Niacinamide 20% has a slightly thicker texture. It also contains different supporting ingredients including meadowsweet, and camellia japonica to help reduce excess oil and offset pro-ageing enzymes that can lead to stubborn, enlarged pores.

Should I use the CLINICAL Niacinamide 20% Treatment, 10% Niacinamide Booster or both?

You should use the Niacinamide 20% if you have advanced concerns such as stretched, sagging pores, orange peel-like texture, or stubborn oil-related bumps. If your concerns are enlarged pores and uneven skin tone, the 10% strength is ideal. If the intensity of your concerns varies over your entire face, you may want to try experimenting with both products.

Can I use Niacinamide 20% Treatment with other products containing niacinamide?

Yes, you can use the Niacinamide 20% Treatment with other niacinamide products including serums and moisturisers, layering them in order from thinnest to thickest texture. You can also alternate their use if you find that suits your skin’s needs.

Why did Paula's Choice formulate another niacinamide product?

The CLINICAL Niacinamide 20% Treatment was the brainchild of our founder, Paula Begoun. Having experienced such great results with the 10% Niacinamide Booster, she wanted to see if doubling the percentage would give her even better results on her most stubborn concerns (persistent clogged pores and bumps). Paula and team added some key supporting ingredients that really make this product a standout for anyone wanting to tackle large pores, rough, bumpy texture and uneven skin tone. The results exceeded expectations and the rest is history.

Can niacinamide cause sensitivity, redness or irritation?

Niacinamide typically doesn’t cause redness, sensitivity or irritation, although some people experience a brief flushing when pure niacinamide and vitamin C are used together. This combination can convert niacinamide to niacin, which may trigger temporary redness. Cosmetic chemists carefully formulate to avoid this concern, and even in a lab setting the conversion requires a significant amount of time and heat before it occurs. For those with a known sensitivity to niacinamide or with extra-sensitive skin in general, we suggest introducing the product slowly for the first two weeks, then increase gradually if desired.

Can I use niacinamide every day?

Yes, you can safely use niacinamide every day. Applying niacinamide products daily will provide the most consistent results.

Is niacinamide better morning or night?

For best results, you can use niacinamide in the morning and at night. You can also alternate its use if you find that works better for you.

What can you not mix with niacinamide?

While there are a lot of myths and misinformation about which ingredients you supposedly can’t mix with niacinamide, research shows that you can use niacinamide with retinol, vitamin C, hydroxy acids and other skin care ingredients safely.

3.8
Rated 3.8 out of 5 stars
Based on 34 reviews
65%would recommend this product
Total 5 star reviews: 19 Total 4 star reviews: 3 Total 3 star reviews: 2 Total 2 star reviews: 6 Total 1 star reviews: 4
Reviews Summary
Customers say this niacinamide serum dramatically improves skin texture and smoothness, with many noticing visible results overnight. Users report reduced pore appearance, clearer skin, and less oiliness when used consistently. The product absorbs well and works effectively when paired with other skincare products. However, some customers find the texture thick and sticky, with a noticeable fishy scent. Several users with sensitive or acne-prone skin experienced breakouts and irritation. Common feedback includes the 20ml bottle size being too small and running out quickly. Many reviews mention the product's effectiveness for evening skin tone and reducing textured skin, though results vary significantly between users.
34 reviews
  • Radha
    Flag of Australia
    Verified Buyer
    I recommend this product
    Pros Non-Greasy, Softens Skin, Lightweight, Soothes Skin
    Cons Irritates Skin, Greasy, Bad Smell, Heavy
    Best Uses Daily Use, Sensitive Skin, Fine Lines/Wrinkles, Enlarged Pores, Uneven Skin Tone
    Describe Yourself Skin Care Professional
    Rated 4 out of 5 stars
    1 week ago
    I would buy it product again

    Im using it daily as an skin care routine .this is verry helpful to deduce my open pore.

  • Bellen
    Flag of Australia
    Verified Buyer
    I recommend this product
    Pros Softens Skin, Moisturises, Lightweight
    Best Uses Daily Use, Enlarged Pores
    Describe Yourself Beauty Conscious
    Rated 5 out of 5 stars
    1 month ago
    A staple in my AM routine

    I use this serum every morning after after my exfoliant and find it helps with my skin texture and complexion. It's become a staple in my AM routine.

  • Gypsy
    Flag of Australia
    Verified Buyer
    I recommend this product
    Pros Non-Greasy, Soothes Skin
    Best Uses Sensitive Skin, Uneven Skin Tone
    Describe Yourself Minimalist
    Rated 5 out of 5 stars
    1 month ago
    I would buy this product again

    I use this product every 2nd night as it is expensive.

    Was recommended by my dermatologist for my rosacea.

    Great for sensitive skin and feels so good on

  • Foxxy
    Flag of Australia
    I do not recommend this product
    Pros Non-Greasy
    Cons Irritates Skin
    Describe Yourself Minimalist
    Rated 1 out of 5 stars
    12 months ago
    I would not buy this product again

    I bought this product as it was advised to use with the vitamin c serum and moisturiser. Unfortunately, after 2 days of application by breakout was out of control and I throw the product away. It was probably not for skin type as I have quiet sensitive skin as well.

    Paula's Choice - Australia
    11 months ago

    Hello! We're sorry this didn't work for your skin. We know not every product works for everyone, so we do offer a 60 day return policy for all products purchased on our site. For future purchases, if needed you can initiate the return in your account online or you can reach out to Client Services for help on the process if something isn't working for your skin as well. They can also give guidance on your routine and help you determine what you could use instead, depending on your concerns. They're always happy to help. -PC

  • Michele
    Flag of Australia
    I recommend this product
    Pros Non-Greasy, Lightweight
    Best Uses Daily Use, Uneven Skin Tone
    Describe Yourself Beauty Conscious
    Rated 5 out of 5 stars
    1 year ago
    I would buy this again

    I use a small amount of this every morning all over my face and neck.